Title : Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala.

Pub. Date : 2021 Aug 29

PMID : 34573170






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A coordinated regulation of several ECM metalloproteinases (e.g., Mmp2; Mmp14), their substrates (e.g., multiple collagen genes and myelin basic protein; Mbp), and a metalloproteinase inhibitor, Reck, suggests a specific mechanism for ECM re-organization in response to chronic alcohol, which may modulate neuronal activity and result in behavioral changes, such as an escalation of alcohol drinking. Alcohols matrix metallopeptidase 14 Rattus norvegicus