Title : Estradiol influences adenosinergic signaling and nonrapid eye movement sleep need in adult female rats.

Pub. Date : 2022 Mar 14

PMID : 34477210






1 Functional Relationships(s)
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1 While these results seemed contradictory, systemically administered E2 blocked the ability of CGS-21680 (adenosine A2A receptor agonist) microinjected into the MnPO to increase NREM sleep suggesting that E2 may block adenosine signaling. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine adenosine A2a receptor Rattus norvegicus