PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34477210-9 2022 While these results seemed contradictory, systemically administered E2 blocked the ability of CGS-21680 (adenosine A2A receptor agonist) microinjected into the MnPO to increase NREM sleep suggesting that E2 may block adenosine signaling. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine 94-103 adenosine A2a receptor Rattus norvegicus 105-127