Title : Lignans from Machilus thunbergii as Thymic Stromal Lymphopoietin Inhibitors.

Pub. Date : 2021 Aug 8

PMID : 34443392






2 Functional Relationships(s)
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1 The 80% methanol extract of Machilus thunbergii bark significantly inhibited the signal transducer and activator of transcription 5 (STAT5) phosphorylation in human mast cell (HMC)-1 cells. Methanol signal transducer and activator of transcription 5A Homo sapiens
2 Among them, two lignans (1 and 2) significantly inhibited STAT5 phosphorylation and TSLP/TSLPR interaction, as determined by ELISA. Lignans signal transducer and activator of transcription 5A Homo sapiens