Title : Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.

Pub. Date : 2021 Sep 20

PMID : 34387696






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The structures reveal a second metal binding site in its beta-CASP domain unique to Artemis, which is amenable to inhibition by compounds including ebselen. Metals cut like homeobox 1 Homo sapiens
2 The structures reveal a second metal binding site in its beta-CASP domain unique to Artemis, which is amenable to inhibition by compounds including ebselen. ebselen cut like homeobox 1 Homo sapiens