Title : Combined inhibition of STAT and Notch signalling effectively suppresses tumourigenesis by inducing apoptosis and inhibiting proliferation, migration and invasion in glioblastoma cells.

Pub. Date : 2021

PMID : 34262659






1 Functional Relationships(s)
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1 STAT5 inhibitor (Pimozide) and STAT3 inhibitor (S3I-201) were individually used in combination with gamma-secretase inhibitor (DAPT), an inhibitor of Notch signalling, in a panel of GBM cells for cell proliferation and epithelial plasticity changes. Pimozide signal transducer and activator of transcription 5A Homo sapiens