Pub. Date : 2021 Oct
PMID : 34237468
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gallic acid attenuates cadmium mediated cardiac hypertrophic remodelling through upregulation of Nrf2 and PECAM-1signalling in rats. | Gallic Acid | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 2 | GA upregulated the expression of Nrf2 (2-fold), HO-1 (3-fold), and PECAM-1 (0.6-fold), which augments the detoxifying enzyme activity and cellular immunity in Cd intoxicated rats. | Cadmium | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 3 | Thus, our results suggest that GA could act as a potential therapeutic agent regulating Nrf2 and PECAM-1 signalling pathways, thereby ameliorating Cd-induced pathological cardiac remodelling. | Gallic Acid | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |