Pub. Date : 1988 May 1
PMID : 3364973
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An antibody directed against the male-specific cytochrome P-450 UT-A decreased androst-4-ene-3,17-dione 16 alpha-hydroxylase activity to 13% of control in hepatic microsomes from untreated rats. | 4-androstene | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 2 | An antibody directed against the male-specific cytochrome P-450 UT-A decreased androst-4-ene-3,17-dione 16 alpha-hydroxylase activity to 13% of control in hepatic microsomes from untreated rats. | 3,17-dione | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 3 | Further, the increased susceptibility of androst-4-ene-3,17-dione 16 alpha-hydroxylase activity to inhibition by an antibody to cytochrome P-450 UT-A, following ferricyanide treatment of microsomes, suggests that this male sexually differentiated enzyme is also complexed after in vivo SKF 525-A dosage. | Androstenedione | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 4 | Further, the increased susceptibility of androst-4-ene-3,17-dione 16 alpha-hydroxylase activity to inhibition by an antibody to cytochrome P-450 UT-A, following ferricyanide treatment of microsomes, suggests that this male sexually differentiated enzyme is also complexed after in vivo SKF 525-A dosage. | hexacyanoferrate III | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 5 | Further, the increased susceptibility of androst-4-ene-3,17-dione 16 alpha-hydroxylase activity to inhibition by an antibody to cytochrome P-450 UT-A, following ferricyanide treatment of microsomes, suggests that this male sexually differentiated enzyme is also complexed after in vivo SKF 525-A dosage. | Proadifen | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |