Title : Nanomolar melatonin influences insulin synthesis and secretion in rat insulinoma INS-1E cells.

Pub. Date : 2020 Oct

PMID : 33571963






1 Functional Relationships(s)
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1 Levels of membrane vesicle trafficking-related proteins including Rab5, GOPC, phospho-caveolin-1, EEA1, and clathrin proteins significantly increased with melatonin treatment above that in control cells without melatonin or glucose treatments, whereas expressions of APPL1 and syntaxin-6 proteins significantly decreased with melatonin treatment. Melatonin adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Rattus norvegicus