Title : Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.

Pub. Date : 2021 Feb 8

PMID : 33351782






4 Functional Relationships(s)
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Protein Name
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1 Mechanistically, we determined that Treg-specific loss of the transcription factor Blimp-1, a driver of IL-10 expression by Tregs, phenocopied the Treg-specific IL-10-deficient mice. treg PR domain containing 1, with ZNF domain Mus musculus
2 Mechanistically, we determined that Treg-specific loss of the transcription factor Blimp-1, a driver of IL-10 expression by Tregs, phenocopied the Treg-specific IL-10-deficient mice. tregs PR domain containing 1, with ZNF domain Mus musculus
3 Mechanistically, we determined that Treg-specific loss of the transcription factor Blimp-1, a driver of IL-10 expression by Tregs, phenocopied the Treg-specific IL-10-deficient mice. treg PR domain containing 1, with ZNF domain Mus musculus
4 Blimp-1-deficient mice were protected from glucose intolerance, insulin resistance and diet-induced obesity (DIO), through increased white adipose tissue browning. Glucose PR domain containing 1, with ZNF domain Mus musculus