Title : USP38 Couples Histone Ubiquitination and Methylation via KDM5B to Resolve Inflammation.

Pub. Date : 2020 Nov

PMID : 33240782






1 Functional Relationships(s)
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1 USP38 specifically removes the monoubiquitin on H2B at lysine 120, which functions as a prerequisite for the subsequent recruitment of demethylase KDM5B to the promoters of proinflammatory cytokines Il6 and Il23a during LPS stimulation. Lysine lysine (K)-specific demethylase 5B Mus musculus