Pub. Date : 2021 Jan
PMID : 33191180
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-regulating inflammation-related factors with suppressing beta-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3. | Sunitinib | B cell leukemia/lymphoma 6 | Mus musculus |
| 2 | These results suggest that sunitinib malate can significantly improve the survival status and inhibit intestinal tumor development in male ApcMin/+ mice, through inhibiting inflammation-related factors, while suppressing beta-cateinin/c-Myc pathway and re-balancing protein levels of Bcl-6 and Caspase-3. | Sunitinib | B cell leukemia/lymphoma 6 | Mus musculus |