| Protein Name | B cell leukemia/lymphoma 6 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12053 |
| Gene Symbol | Bcl6 |
| UniProt | P41183 (BCL6_MOUSE), Q544F9 (Q544F9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
57
Total Number of Articles : 48 |
Description |
B cell leukemia/lymphoma 6 |
| Gene Summary |
Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of lymphocyte activation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor). [provided by Alliance of Genome Resources, Jul 2025] |
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