Pub. Date : 2020 Aug 20
PMID : 32819407
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: CBH induced by 2VO initiated microglial/macrophage activation in the rat hippocampus from 1 week to 8 weeks, as evaluated by increased ratio of (CD68+ and CD206+)/Iba-1 immunofluorescence. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | Cd68 molecule | Rattus norvegicus |
| 2 | RESULTS: CBH induced by 2VO initiated microglial/macrophage activation in the rat hippocampus from 1 week to 8 weeks, as evaluated by increased ratio of (CD68+ and CD206+)/Iba-1 immunofluorescence. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | allograft inflammatory factor 1 | Rattus norvegicus |
| 3 | CONCLUSIONS: Our findings conclude that downregulation of miR-195 in the hippocampus is involved in CBH-induced microglial/macrophage polarization towards M1 phenotype by governing communication between neurons and microglia through the regulation of CX3CL1 and CX3CR1 signaling. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | microRNA 195a | Mus musculus |
| 4 | CONCLUSIONS: Our findings conclude that downregulation of miR-195 in the hippocampus is involved in CBH-induced microglial/macrophage polarization towards M1 phenotype by governing communication between neurons and microglia through the regulation of CX3CL1 and CX3CR1 signaling. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | chemokine (C-X3-C motif) ligand 1 | Mus musculus |
| 5 | CONCLUSIONS: Our findings conclude that downregulation of miR-195 in the hippocampus is involved in CBH-induced microglial/macrophage polarization towards M1 phenotype by governing communication between neurons and microglia through the regulation of CX3CL1 and CX3CR1 signaling. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | chemokine (C-X3-C motif) receptor 1 | Mus musculus |
| 6 | This indicates that miR-195 may provide a new strategy for clinical prevention and treatment of CBH. | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | microRNA 195a | Mus musculus |