Protein Name C-X3-C motif chemokine receptor 1
Organism Mus musculus
Gene ID 13051
Gene Symbol

Cx3cr1

UniProt Q9Z0D9 (CX3C1_MOUSE), Q543X3 (Q543X3_MOUSE)
Relationships Total Number of functionally related compound(s) : 146
Total Number of Articles : 157
Description

C-X3-C motif chemokine receptor 1

Gene Summary

Enables C-X3-C chemokine binding activity and C-X3-C chemokine receptor activity. Involved in several processes, including antifungal innate immune response; central nervous system development; and synapse organization. Located in cell surface. Is expressed in several structures, including brain; colon; genitourinary system; head mesenchyme; and meninges. Used to study age related macular degeneration 12. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • CX3C chemokine receptor 1
  • C-X3-C CKR-1
  • chemokine (C-X3-C motif) receptor 1
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Properties