Title : In vitro assessment of the photo(geno)toxicity associated with Lapatinib, a Tyrosine Kinase inhibitor.

Pub. Date : 2021 Jan

PMID : 32815004






1 Functional Relationships(s)
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1 Although hepatotoxicity is its main side effect, it makes sense to investigate the ability of LAP to induce photosensitivity reactions bearing in mind that BRAF (serine/threonine-protein kinase B-Raf) inhibitors display a considerable phototoxic potential and that afloqualone, a quinazoline-marketed drug, causes photodermatosis. afloqualone B-Raf proto-oncogene, serine/threonine kinase Homo sapiens