Title : miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis.

Pub. Date : 2020 Jul

PMID : 32335272






2 Functional Relationships(s)
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1 Remarkably, we showed that administration of an antisense oligonucleotide (ASO) inhibitor of miR-129-5p to an ALS animal model, SOD1 (G93A) mice, result in a significant increase in survival and improved the neuromuscular phenotype in treated mice. Oligonucleotides microRNA 1295a Homo sapiens
2 Remarkably, we showed that administration of an antisense oligonucleotide (ASO) inhibitor of miR-129-5p to an ALS animal model, SOD1 (G93A) mice, result in a significant increase in survival and improved the neuromuscular phenotype in treated mice. Oligonucleotides, Antisense microRNA 1295a Homo sapiens