Title : Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment.

Pub. Date : 2020 Jun 11

PMID : 32321643






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Incubation with E-4031, but not lumacaftor, rescued defective hERG-T634S channel trafficking and IhERG density. E 4031 ETS transcription factor ERG Homo sapiens