Pub. Date : 2020 May
PMID : 32036216
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Trelagliptin succinate: DPP-4 inhibitor to improve insulin resistance in adipocytes. | trelagliptin | dipeptidylpeptidase 4 | Mus musculus |
| 2 | Trelagliptin inhibits the enzyme dipeptidyl-4 (DPP-4) to treat type 2 diabetes and it may possess the potential to improve insulin resistance. | trelagliptin | dipeptidylpeptidase 4 | Mus musculus |
| 3 | Trelagliptin inhibits the enzyme dipeptidyl-4 (DPP-4) to treat type 2 diabetes and it may possess the potential to improve insulin resistance. | trelagliptin | dipeptidylpeptidase 4 | Mus musculus |
| 4 | Our results demonstrated that trelagliptin succinate increased the expression of AKT, P-AKT, IRS-1 and P-IRS-1 in the PI-3K/AKT insulin signaling pathway. | trelagliptin | thymoma viral proto-oncogene 1 | Mus musculus |
| 5 | Our results demonstrated that trelagliptin succinate increased the expression of AKT, P-AKT, IRS-1 and P-IRS-1 in the PI-3K/AKT insulin signaling pathway. | trelagliptin | insulin receptor substrate 1 | Mus musculus |
| 6 | Our results demonstrated that trelagliptin succinate increased the expression of AKT, P-AKT, IRS-1 and P-IRS-1 in the PI-3K/AKT insulin signaling pathway. | trelagliptin | insulin receptor substrate 1 | Mus musculus |
| 7 | Our results demonstrated that trelagliptin succinate increased the expression of AKT, P-AKT, IRS-1 and P-IRS-1 in the PI-3K/AKT insulin signaling pathway. | trelagliptin | thymoma viral proto-oncogene 1 | Mus musculus |
| 8 | In conclusion, our study suggested that trelagliptin succinate improved insulin resistance in adipocytes via regulation of PI-3K/AKT/GLUT4 insulin signaling pathway. | trelagliptin | thymoma viral proto-oncogene 1 | Mus musculus |
| 9 | In conclusion, our study suggested that trelagliptin succinate improved insulin resistance in adipocytes via regulation of PI-3K/AKT/GLUT4 insulin signaling pathway. | trelagliptin | solute carrier family 2 (facilitated glucose transporter), member 4 | Mus musculus |