Pub. Date : 2020 Apr
PMID : 32018068
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Previous studies showed that GTS-21, a selective alpha 7 nAchR agonist, can trigger anti-inflammatory effects and improve the survival of septic animals. | 3-(2,4-dimethoxybenzylidene)anabaseine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | The administration of GTS-21 inhibited pro-inflammatory cytokine production and hepatic enzymatic marker expression, promoted the expression of LC3-II, Atg7, Atg5, and decreased the expression of p62, which could be reversed by alpha-BGT treatment. | 3-(2,4-dimethoxybenzylidene)anabaseine | autophagy related 7 | Mus musculus |
| 3 | The administration of GTS-21 inhibited pro-inflammatory cytokine production and hepatic enzymatic marker expression, promoted the expression of LC3-II, Atg7, Atg5, and decreased the expression of p62, which could be reversed by alpha-BGT treatment. | 3-(2,4-dimethoxybenzylidene)anabaseine | autophagy related 5 | Mus musculus |
| 4 | The administration of GTS-21 inhibited pro-inflammatory cytokine production and hepatic enzymatic marker expression, promoted the expression of LC3-II, Atg7, Atg5, and decreased the expression of p62, which could be reversed by alpha-BGT treatment. | 3-(2,4-dimethoxybenzylidene)anabaseine | nucleoporin 62 | Mus musculus |