Title : Retinoid X receptor ligand regulates RXRα/Nur77-dependent apoptosis via modulating its nuclear export and mitochondrial targeting.

Pub. Date : 2017

PMID : 31966420






2 Functional Relationships(s)
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1 We demonstrated that Abeta peptide and H2O2 treatment could result in the translocation of RXRalpha and Nur77 from the nucleus to the mitochondria, and the ligand of RXR, 9-cis-RA, treatment can block the above phenomenon. Water retinoid X receptor alpha Homo sapiens
2 We demonstrated that Abeta peptide and H2O2 treatment could result in the translocation of RXRalpha and Nur77 from the nucleus to the mitochondria, and the ligand of RXR, 9-cis-RA, treatment can block the above phenomenon. retinol acetate retinoid X receptor alpha Homo sapiens