Title : XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/β-catenin signaling dependent way.

Pub. Date : 2019 Oct 15

PMID : 31499069






1 Functional Relationships(s)
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1 KEY FINDINGS: We conclude that XQ-1H preserved the motor functions, limited apoptosis, and concomitantly promoted neurogenesis-related protein expression by Wnt signaling-dependently compromising GSK3beta/Caspase-3 activity and enhancing the expression of Wnt1/beta-catenin/Neuro D1/Cyclin D1 and Bcl-xL. xq-1h neurogenic differentiation 1 Mus musculus