Protein Name neurogenic differentiation 1
Organism Mus musculus
Gene ID 18012
Gene Symbol

Neurod1

UniProt Q60867 (NDF1_MOUSE)
Relationships Total Number of functionally related compound(s) : 36
Total Number of Articles : 42
Description

neurogenic differentiation 1

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in several processes, including central nervous system development; regulation of DNA-templated transcription; and regulation of apoptotic process. Acts upstream of or within several processes, including endocrine pancreas development; negative regulation of receptor signaling pathway via JAK-STAT; and signal transduction involved in regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; neurogenic placode; and sensory organ. Used to study type 1 diabetes mellitus 7. Human ortholog(s) of this gene implicated in glucose intolerance; hyperglycemia; maturity-onset diabetes of the young type 6; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human NEUROD1 (neuronal differentiation 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • neurogenic differentiation factor 1
  • beta-cell E-box transcriptional activator 2
  • BETA2
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Properties