Title : The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.

Pub. Date : 2019 Sep

PMID : 31463593






1 Functional Relationships(s)
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1 Furthermore, our in vitro reconstitution experiments with Dph1-Dph2 mutants suggested that the Dph1 cluster serves a catalytic role, while the Dph2 cluster facilitates the reduction of the Dph1 cluster by the physiological reducing system Dph3/Cbr1/NADH. NAD diphthamide biosynthesis 3 Homo sapiens