Pub. Date : 2019 Jun 13
PMID : 31196136
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: Expression of SIRT7 in 17 paired paraffin-embedded HCC tissues and adjacent nontumoral liver tissues was examined by immunohistochemistry and Western blot. | Paraffin | sirtuin 7 | Homo sapiens |
| 2 | Depletion of SIRT7 from multiple liver cancer cell lines significantly increased doxorubicin toxicity while overexpression of SIRT7 largely abolished doxorubicin induced apoptosis. | Doxorubicin | sirtuin 7 | Homo sapiens |
| 3 | Depletion of SIRT7 from multiple liver cancer cell lines significantly increased doxorubicin toxicity while overexpression of SIRT7 largely abolished doxorubicin induced apoptosis. | Doxorubicin | sirtuin 7 | Homo sapiens |
| 4 | At the molecular level, we observed that SIRT7 interacts with and induces deacetylation of p53 at lysines 320 and 373. | Lysine | sirtuin 7 | Homo sapiens |