Title : Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.

Pub. Date : 2019 Jul

PMID : 31051182






1 Functional Relationships(s)
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1 Phosphodiesterase type 3 (PDE3) inhibitors block the cAMP hydrolyzing activity of both PDE3 isoforms, PDE3A and PDE3B, which have distinct roles in the heart. Cyclic AMP phosphodiesterase 3A, cGMP inhibited Mus musculus