Protein Name phosphodiesterase 3A, cGMP inhibited
Organism Mus musculus
Gene ID 54611
Gene Symbol

Pde3a

UniProt Q9Z0X4 (PDE3A_MOUSE), B2RR84 (B2RR84_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 35
Description

phosphodiesterase 3A, cGMP inhibited

Gene Summary

Enables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including oocyte maturation; positive regulation of oocyte development; and regulation of meiotic nuclear division. Located in cytosol and membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Orthologous to human PDE3A (phosphodiesterase 3A). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
  • CGI-PDE A
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase A
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Properties