Title : IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-κB signaling pathway to increase of major vault protein.

Pub. Date : 2019 Jul

PMID : 31044552






5 Functional Relationships(s)
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Protein Name
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1 IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-kappaB signaling pathway to increase of major vault protein. Cisplatin interleukin 25 Homo sapiens
2 In this study, we found that both IL-25 and MVP were elevated expressed in cisplatin-resistant lung adenocarcinoma cell line (A549/CDDP). Cisplatin interleukin 25 Homo sapiens
3 In this study, we found that both IL-25 and MVP were elevated expressed in cisplatin-resistant lung adenocarcinoma cell line (A549/CDDP). Cisplatin interleukin 25 Homo sapiens
4 Silencing of IL-25 resulted in down-regulation of MVP expression and reduced cisplatin tolerance of A549/CDDP cells. Cisplatin interleukin 25 Homo sapiens
5 Overexpression of IL-25 resulted in increase of MVP expression and the cisplatin tolerance in A549 cells. Cisplatin interleukin 25 Homo sapiens