Protein Name interleukin 25
Organism Homo sapiens
Gene ID 64806
Gene Symbol

IL25

UniProt Q9H293 (IL25_HUMAN)
Relationships Total Number of functionally related compound(s) : 64
Total Number of Articles : 59
Description

interleukin 25

Gene Summary

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

synonyms
  • interleukin-25
  • interleukin-17E
  • IL17E
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Properties