Pub. Date : 2019 Jul
PMID : 30933929
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phoenixin acts through its receptor, G protein-coupled receptor 173 (GPR173), to activate the cAMP/PKA pathway leading to the phosphorylation of CREB (pCREB). | Cyclic AMP | G protein-coupled receptor 173 | Homo sapiens |
| 2 | Phoenixin acts through its receptor, G protein-coupled receptor 173 (GPR173), to activate the cAMP/PKA pathway leading to the phosphorylation of CREB (pCREB). | Cyclic AMP | G protein-coupled receptor 173 | Homo sapiens |
| 3 | Taken together, our data demonstrate that phoenixin is an intraovarian factor that promotes follicular growth through its receptor GPR173 by accelerating proliferation of GCs, inducing E2 production, and increasing the expression of genes related to follicle development. | phoenixin | G protein-coupled receptor 173 | Homo sapiens |