Pub. Date : 2019 Apr
PMID : 30723180
15 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arabidopsis (Arabidopsis thaliana) GARP (Golden2, ARR-B, Psr1) family transcription factors, GOLDEN2-LIKE1 and -2 (GLK1/2), function in different biological processes; however, whether and how these transcription factors modulate the response to abscisic acid (ABA) remain unknown. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 2 | Arabidopsis (Arabidopsis thaliana) GARP (Golden2, ARR-B, Psr1) family transcription factors, GOLDEN2-LIKE1 and -2 (GLK1/2), function in different biological processes; however, whether and how these transcription factors modulate the response to abscisic acid (ABA) remain unknown. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 3 | In this study, we used a glk1 glk2 double mutant to examine the role of GLK1/2 in the ABA response. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 4 | The glk1 glk2 double mutant displayed ABA-hypersensitive phenotypes during seed germination and seedling development and an osmotic stress-resistant phenotype during seedling development. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 5 | Genome-wide RNA sequencing analysis of the glk1 glk2 double mutant revealed that GLK1/2 regulate several ABA-responsive genes, including WRKY40, in the presence of ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 6 | Genome-wide RNA sequencing analysis of the glk1 glk2 double mutant revealed that GLK1/2 regulate several ABA-responsive genes, including WRKY40, in the presence of ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 7 | Genome-wide RNA sequencing analysis of the glk1 glk2 double mutant revealed that GLK1/2 regulate several ABA-responsive genes, including WRKY40, in the presence of ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 8 | Genome-wide RNA sequencing analysis of the glk1 glk2 double mutant revealed that GLK1/2 regulate several ABA-responsive genes, including WRKY40, in the presence of ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 9 | Additionally, RNA sequencing analysis of the glk1 glk2 double mutant and wrky40 single mutant revealed that GLK1/2 and WRKY40 control a common set of downstream target genes in response to ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 10 | Additionally, RNA sequencing analysis of the glk1 glk2 double mutant and wrky40 single mutant revealed that GLK1/2 and WRKY40 control a common set of downstream target genes in response to ABA. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 11 | Furthermore, results of a genetic interaction test showed that the glk1 glk2 wrky40 triple mutant displayed similar ABA hypersensitivity to the wrky40 single mutant and the glk1 glk2 double mutant, while the glk1 glk2 wrky40 abi5-c (ABI5 CRISPR/Cas9 mutant) quadruple mutant displayed similar ABA hyposensitivity to the abi5-7 single mutant. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 12 | Furthermore, results of a genetic interaction test showed that the glk1 glk2 wrky40 triple mutant displayed similar ABA hypersensitivity to the wrky40 single mutant and the glk1 glk2 double mutant, while the glk1 glk2 wrky40 abi5-c (ABI5 CRISPR/Cas9 mutant) quadruple mutant displayed similar ABA hyposensitivity to the abi5-7 single mutant. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 13 | Furthermore, results of a genetic interaction test showed that the glk1 glk2 wrky40 triple mutant displayed similar ABA hypersensitivity to the wrky40 single mutant and the glk1 glk2 double mutant, while the glk1 glk2 wrky40 abi5-c (ABI5 CRISPR/Cas9 mutant) quadruple mutant displayed similar ABA hyposensitivity to the abi5-7 single mutant. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 14 | Furthermore, results of a genetic interaction test showed that the glk1 glk2 wrky40 triple mutant displayed similar ABA hypersensitivity to the wrky40 single mutant and the glk1 glk2 double mutant, while the glk1 glk2 wrky40 abi5-c (ABI5 CRISPR/Cas9 mutant) quadruple mutant displayed similar ABA hyposensitivity to the abi5-7 single mutant. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |
| 15 | Based on these results, we propose that the GLK1/2-WRKY40 transcription module plays a negative regulatory role in the ABA response. | Abscisic Acid | GBF's pro-rich region-interacting factor 1 | Arabidopsis thaliana |