Title : 10‑Hydroxycamptothecin induces apoptosis in human fibroblasts by regulating miRNA‑23b‑3p expression.

Pub. Date : 2019 Apr

PMID : 30720099






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 10-Hydroxycamptothecin induces apoptosis in human fibroblasts by regulating miRNA-23b-3p expression. 10-hydroxycamptothecin microRNA 23b Homo sapiens
2 In addition, the miR-23b-3p expression level in human fibroblasts was examined following HCPT treatment. 10-hydroxycamptothecin microRNA 23b Homo sapiens
3 The results demonstrated that HCPT treatment notably increased miR-23b-3p expression levels and accelerated fibroblast apoptosis. 10-hydroxycamptothecin microRNA 23b Homo sapiens
4 Therefore, upregulation of miR-23b-3p expression was demonstrated to promote fibroblast apoptosis, consistently with the effects of HCPT. 10-hydroxycamptothecin microRNA 23b Homo sapiens
5 The results of the present study indicated that HCPT may induce fibroblast apoptosis by regulating miR-23b-3p expression. 10-hydroxycamptothecin microRNA 23b Homo sapiens