Title : TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress.

Pub. Date : 2019 Jan

PMID : 30538118






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Since TIAR retains CDK1 in GMGs and attenuates CDK1 activity, we propose that the assembly of GMGs may represent a so far unrecognized mechanism that contributes to the activation of the G2/M checkpoint in mammalian cells. gmgs TIA1 cytotoxic granule associated RNA binding protein like 1 Homo sapiens
2 Since TIAR retains CDK1 in GMGs and attenuates CDK1 activity, we propose that the assembly of GMGs may represent a so far unrecognized mechanism that contributes to the activation of the G2/M checkpoint in mammalian cells. gmgs TIA1 cytotoxic granule associated RNA binding protein like 1 Homo sapiens