Protein Name TIA1 cytotoxic granule associated RNA binding protein like 1
Organism Homo sapiens
Gene ID 7073
Gene Symbol

TIAL1

UniProt Q01085 (TIAR_HUMAN), Q49AS9 (Q49AS9_HUMAN)
Relationships Total Number of functionally related compound(s) : 45
Total Number of Articles : 30
Description

TIA1 cytotoxic granule associated RNA binding protein like 1

Gene Summary

The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]

synonyms
  • nucleolysin TIAR
  • T-cluster binding protein
  • TIA-1-related nucleolysin
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Properties