Pub. Date : 2019 Mar
PMID : 30521373
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | MicroRNA-129-5p is regulated by choline availability and controls EGF receptor synthesis and neurogenesis in the cerebral cortex. | Choline | microRNA 1295a | Homo sapiens |
2 | Specifically, we found that low choline (LC) availability led to the upregulation of miR-129-5p expression in cortical NPCs in vitro and in vivo, causing the downregulation of EGFR and thereby disrupting NPC self-renewal and cortical neurogenesis. | Choline | microRNA 1295a | Homo sapiens |