Pub. Date : 2018 Dec 1
PMID : 30466623
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Allicin improves the function of cardiac microvascular endothelial cells by increasing PECAM-1 in rats with cardiac hypertrophy. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 2 | Meanwhile, allicin enhanced the migration and angiogenesis ability of CMECs, activated PECAM-1-PI3K-AKT-eNOS signaling pathway, however, the role of allicin was disappear after PECAM-1 was silenced. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 3 | Meanwhile, allicin enhanced the migration and angiogenesis ability of CMECs, activated PECAM-1-PI3K-AKT-eNOS signaling pathway, however, the role of allicin was disappear after PECAM-1 was silenced. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 4 | Meanwhile, allicin enhanced the migration and angiogenesis ability of CMECs, activated PECAM-1-PI3K-AKT-eNOS signaling pathway, however, the role of allicin was disappear after PECAM-1 was silenced. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 5 | Under 10 dyn/cm2 condition, allicin advanced the modification ability of CMECs"s shear-adaptation by activating PECAM-1. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |
| 6 | CONCLUSION: Allicin provided cardioprotection for CH rats by improving the function of CMECs through increasing the expression of PECAM-1. | allicin | platelet and endothelial cell adhesion molecule 1 | Rattus norvegicus |