Title : Counteraction of denaturant-induced protein unfolding is a general property of stabilizing agents.

Pub. Date : 2018 Nov 28

PMID : 30451257






1 Functional Relationships(s)
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1 DSC measurements on RNase A at neutral pH show that five stabilizing agents, namely trimethylamine N-oxide, glucose, sucrose, betaine and sodium sulfate, can counteract the destabilizing action of urea, sodium perchlorate, guanidinium chloride and guanidinium thiocyanate. guanidine thiocyanate ribonuclease A family member 1, pancreatic Homo sapiens