Title : The atlastin membrane anchor forms an intramembrane hairpin that does not span the phospholipid bilayer.

Pub. Date : 2018 Nov 30

PMID : 30287684






1 Functional Relationships(s)
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1 Here, we examined several Drosophila-human atlastin chimeras to identify functional domains of human atlastin-1 in vitro Although all chimeras could hydrolyze GTP, only chimeras containing the human C-terminal tail, hydrophobic segments, or both could fuse membranes in vitro We also determined that co-reconstitution of atlastin with reticulon does not influence GTPase activity or membrane fusion. Guanosine Triphosphate atlastin GTPase 1 Homo sapiens