Title : Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.

Pub. Date : 2018 Jul 19

PMID : 29983320






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutations in the human N7-methylguanosine (m7G) methyltransferase complex METTL1/WDR4 cause primordial dwarfism and brain malformation, yet the molecular and cellular function in mammals is not well understood. 7-methylguanosine WD repeat domain 4 Homo sapiens