| Protein Name | WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10785 |
| Gene Symbol | WDR4 |
| UniProt | P57081 (WDR4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 4 |
Description |
WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit |
| Gene Summary |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |
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| Properties | |