Pub. Date : 1988 Dec 1
PMID : 2974066
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Specific inhibition of lymphokine biosynthesis and autocrine growth using antisense oligonucleotides in Th1 and Th2 helper T cell clones. | Oligonucleotides | heart and neural crest derivatives expressed 2 | Mus musculus |
| 2 | We have used synthetic oligonucleotides complementary to the 5" end of mouse IL-2 and IL-4 to specifically block the biosynthesis of IL-2 or IL-4 in two murine helper T cell clones from the Th1 or Th2 subset. | Oligonucleotides | heart and neural crest derivatives expressed 2 | Mus musculus |
| 3 | In parallel experiments, the antisense IL-4 oligonucleotide blocked the proliferation of the Th2 clone and not the proliferation of the Th1 clone. | Oligonucleotides | heart and neural crest derivatives expressed 2 | Mus musculus |