Pub. Date : 2018 Feb 15
PMID : 29452640
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs. | Serine | serine hydroxymethyltransferase 2 | Homo sapiens |
| 2 | Using genetic screens, we find that the mitochondrial serine hydroxymethyltransferase (SHMT2) is required for robust mitochondrial oxygen consumption and low glucose proliferation. | Oxygen | serine hydroxymethyltransferase 2 | Homo sapiens |
| 3 | Using genetic screens, we find that the mitochondrial serine hydroxymethyltransferase (SHMT2) is required for robust mitochondrial oxygen consumption and low glucose proliferation. | Oxygen | serine hydroxymethyltransferase 2 | Homo sapiens |
| 4 | Using genetic screens, we find that the mitochondrial serine hydroxymethyltransferase (SHMT2) is required for robust mitochondrial oxygen consumption and low glucose proliferation. | Glucose | serine hydroxymethyltransferase 2 | Homo sapiens |
| 5 | Using genetic screens, we find that the mitochondrial serine hydroxymethyltransferase (SHMT2) is required for robust mitochondrial oxygen consumption and low glucose proliferation. | Glucose | serine hydroxymethyltransferase 2 | Homo sapiens |
| 6 | SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. | Carbon | serine hydroxymethyltransferase 2 | Homo sapiens |
| 7 | SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. | 5,6,7,8-tetrahydrofolic acid | serine hydroxymethyltransferase 2 | Homo sapiens |
| 8 | SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. | 5,6,7,8-tetrahydrofolic acid | serine hydroxymethyltransferase 2 | Homo sapiens |
| 9 | SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. | Carbon | serine hydroxymethyltransferase 2 | Homo sapiens |