Pub. Date : 2018 Jan
PMID : 29434699
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neuroprotective effect of (-)-epigallocatechin-3-gallate on autoimmune thyroiditis in a rat model by an anti-inflammation effect, anti-apoptosis and inhibition of TRAIL signaling pathway. | epigallocatechin gallate | TNF superfamily member 10 | Rattus norvegicus |
| 2 | In addition, pretreatment with EGCG significantly increased B-cell lymphoma-2 protein expression, and suppressed caspase-3 activity and TNF-alpha-related apoptosis-inducing ligand (TRAIL) protein expression levels in the AIT model rats. | epigallocatechin gallate | TNF superfamily member 10 | Rattus norvegicus |
| 3 | In addition, pretreatment with EGCG significantly increased B-cell lymphoma-2 protein expression, and suppressed caspase-3 activity and TNF-alpha-related apoptosis-inducing ligand (TRAIL) protein expression levels in the AIT model rats. | epigallocatechin gallate | TNF superfamily member 10 | Rattus norvegicus |
| 4 | In conclusion, these results suggested that the neuroprotective effect of EGCG protects against AIT through its anti-inflammatory ability, anti-apoptosis and TRAIL signaling pathway in model rats, and it may be used as a therapeutic agent against AIT caused by inflammation. | epigallocatechin gallate | TNF superfamily member 10 | Rattus norvegicus |