Protein Name TNF superfamily member 10
Organism Rattus norvegicus
Gene ID 246775
Gene Symbol

Tnfsf10

UniProt E9PU84 (E9PU84_RAT)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 50
Description

TNF superfamily member 10

Gene Summary

Predicted to enable several functions, including TRAIL binding activity; signaling receptor binding activity; and zinc ion binding activity. Involved in male gonad development; positive regulation of apoptotic process; and response to insulin. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. Biomarker of osteoarthritis and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF superfamily member 10). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tumor necrosis factor ligand superfamily member 10
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand 6a
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Properties