Pub. Date : 2018 Jul
PMID : 29388696
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with caffeic acid phenethyl ester (CAPE), a potent and specific inhibitor that suppresses the translocation of NF-kappaB p65 from the cytoplasm to the nucleus, resulted in decreased levels of RBM3 mRNA and protein and increased incidence of apoptosis despite cells were cultured under hypothermic conditions. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |
| 2 | Treatment with caffeic acid phenethyl ester (CAPE), a potent and specific inhibitor that suppresses the translocation of NF-kappaB p65 from the cytoplasm to the nucleus, resulted in decreased levels of RBM3 mRNA and protein and increased incidence of apoptosis despite cells were cultured under hypothermic conditions. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |
| 3 | Overexpression of RBM3 abolished the induction of apoptosis in cells treated with CAPE, indicating that NF-kappaB p65-upregulated RBM3 expression is necessary for the suppression of apoptosis. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |
| 4 | Overexpression of RBM3 abolished the induction of apoptosis in cells treated with CAPE, indicating that NF-kappaB p65-upregulated RBM3 expression is necessary for the suppression of apoptosis. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |
| 5 | Conversely, experiments with cells deficient in RBM3 supported the finding demonstrating that the CAPE-mediated loss of RBM3 induced apoptosis. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |
| 6 | Conversely, experiments with cells deficient in RBM3 supported the finding demonstrating that the CAPE-mediated loss of RBM3 induced apoptosis. | caffeic acid phenethyl ester | RNA binding motif protein 3 | Homo sapiens |