Title : Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis.

Pub. Date : 2018 Jan 10

PMID : 29321536






2 Functional Relationships(s)
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1 Patients with high expression of genes that control the metabolic cycle of tetrahydrofolate (THF) in mitochondria, SHMT2, MTHFD2, and ALDH1L2, have a shorter overall survival rate compared with patients with low expression of these genes. 5,6,7,8-tetrahydrofolic acid serine hydroxymethyltransferase 2 Homo sapiens
2 Patients with high expression of genes that control the metabolic cycle of tetrahydrofolate (THF) in mitochondria, SHMT2, MTHFD2, and ALDH1L2, have a shorter overall survival rate compared with patients with low expression of these genes. 5,6,7,8-tetrahydrofolic acid serine hydroxymethyltransferase 2 Homo sapiens