Title : Fluorescence sensing platform based on ruthenium(II) complexes as high 3S (sensitivity, specificity, speed) and "on-off-on" sensors for the miR-185 detection.

Pub. Date : 2018 Mar 1

PMID : 29310291






1 Functional Relationships(s)
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1 It was found that all complexes can form sensing platform for the detection of the complementary target miR-185 through the introduction of carboxyfluorescein (FAM) labeled single stranded DNA (P-DNA), giving the detection limits of 0.42nM for Ru 1, 0.28nM for Ru 2, 0.32nM for Ru 3, 0.85nM for Ru 4, all with instantaneous detection time in 1min. 6-carboxyfluorescein Scm like with four mbt domains 1 Homo sapiens