Title : Alcohol withdrawal upregulates mRNA encoding for CaV2.1-α1 subunit in the rat inferior colliculus.

Pub. Date : 2018 Feb

PMID : 29277284






3 Functional Relationships(s)
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1 Alcohol withdrawal upregulates mRNA encoding for CaV2.1-alpha1 subunit in the rat inferior colliculus. Alcohols calcium voltage-gated channel subunit alpha1 A Rattus norvegicus
2 Here, we probe changes in mRNA and protein expression of the pore-forming CaV2.1-alpha1 (P/Q-type) subunits in IC neurons during the course of alcohol withdrawal-induced seizures (AWSs). Alcohols calcium voltage-gated channel subunit alpha1 A Rattus norvegicus
3 Compared to control-treated rats, the mRNA levels of the CaV2.1-alpha1 subunit were increased 1.9-fold and 2.1-fold at 3 and 24 h, respectively; change in mRNA expression was nonsignificant at 48 h following alcohol withdrawal. Alcohols calcium voltage-gated channel subunit alpha1 A Rattus norvegicus