Title : Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.

Pub. Date : 2017

PMID : 29213353






6 Functional Relationships(s)
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1 Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1alpha Pathway. Resveratrol sirtuin 1 Bos taurus
2 Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1alpha Pathway. Reactive Oxygen Species sirtuin 1 Bos taurus
3 High glucose was found to decrease the levels of phosphorylated AMP-activated protein kinase (p-AMPK), which was accompanied by increased levels of Sirt1 and PGC-1alpha. Glucose sirtuin 1 Bos taurus
4 In summary, the current study demonstrates that RSV is effective against high glucose-induced cellular apoptosis and its action is exerted via the inhibition of ROS/AMPK/Sirt1/PGC-1alpha pathway. Resveratrol sirtuin 1 Bos taurus
5 In summary, the current study demonstrates that RSV is effective against high glucose-induced cellular apoptosis and its action is exerted via the inhibition of ROS/AMPK/Sirt1/PGC-1alpha pathway. Glucose sirtuin 1 Bos taurus
6 In summary, the current study demonstrates that RSV is effective against high glucose-induced cellular apoptosis and its action is exerted via the inhibition of ROS/AMPK/Sirt1/PGC-1alpha pathway. Reactive Oxygen Species sirtuin 1 Bos taurus