Pub. Date : 2018 Jan 5
PMID : 29133031
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. | Chloroquine | TNF superfamily member 10 | Rattus norvegicus |
| 2 | This study aimed to evaluate chloroquine"s (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX). | Chloroquine | TNF superfamily member 10 | Rattus norvegicus |
| 3 | This study aimed to evaluate chloroquine"s (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX). | Chloroquine | TNF superfamily member 10 | Rattus norvegicus |
| 4 | This study aimed to evaluate chloroquine"s (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX). | Thioacetamide | TNF superfamily member 10 | Rattus norvegicus |
| 5 | CQ induced apoptosis via upregulation of TRAIL/TRAILR2, caspase-8, caspase-3 and caspase-8 genes and downregulation of BCL-2 gene. | Chloroquine | TNF superfamily member 10 | Rattus norvegicus |